What happened: No other NFL team has more than 16 players on its camp injury list. Kansas City is also managing health concerns involving key players ahead of Week 1.
Why it matters: Both clubs are approaching their regular-season openers with availability decisions pending. San Francisco's injury volume complicates final roster choices and depth planning.
By the numbers: San Francisco's 25 listed injuries exceed the next-highest NFL total by at least nine, a gap of more than 56%.
What to watch: Practice participation and official Week 1 designations will provide the next indicators. Final roster moves could also reveal where each club needs reinforcements.