What happened: Offensive linemen Kayode Awosika and Trey Pipkins III joined defensive tackle Justin Eboigbe and linebacker Denzel Perryman on the final status designations. The updates leave multiple starters on both sides of the ball uncertain for Sunday's road test.

Why it matters: Los Angeles is seeking its first victory following a 44-22 loss to the Houston Texans on Nov. 8. A ninth consecutive defeat would deepen early-season strain for the Los Angeles Chargers as injuries mount across the active roster.

What to watch: Official inactive lists will be finalized 90 minutes prior to kickoff in Baltimore. Pre-game evaluations on Sunday morning will determine the availability of the questionable starters.