What happened: Indianapolis ruled out Keenan Allen with a groin injury. Buffalo agreed to a two-year, $5 million extension with Joe Andreessen.

Why it matters: Allen's absence removes a veteran target from the Colts' offense and forces Indianapolis to reshuffle its receiving workload. The Bills used the move to keep Joe Andreessen under contract as he plays his third NFL season.

What to watch: Indianapolis' next injury update will show whether Allen can return quickly from the groin issue. Buffalo's next roster checkpoints will show how the new deal fits into its linebacker plans.