What happened: The performance came in Week 10 on Nov. 15, 2010, with Philadelphia scoring on its first snap from scrimmage. The Eagles led 35-0 after one quarter.
Why it matters: The 31-point win remains a franchise benchmark for dual-threat quarterback play. Philadelphia's Week 1 result will immediately count in the NFC East race.
By the numbers: The quarterback totaled 413 yards: 333 passing and 80 rushing. Four touchdowns came through the air and two on the ground.
What to watch: Kickoff is scheduled for Sept. 13 at 4:25 p.m. ET on FOX and FOX One, with streaming on NFL+.