What happened: Jacksonville Jaguars defensive tackle DaVon Hamilton suffered a knee injury and safety Eric Murray sustained an elbow injury during Sunday's game against the Indianapolis Colts. Both defenders exited the contest and were ruled out from returning.

Why it matters: The injuries test Jacksonville's defensive depth as the front office evaluates its roster after reports that the Jaguars seek defensive line help before the trade deadline. Hamilton's exit weakens the interior rotation, while Murray's departure strains secondary coverage.

What to watch: Jacksonville will monitor medical evaluations on Hamilton and Murray ahead of upcoming practice sessions. The team is expected to provide status updates on both players later in the week.