What happened: Jamal Adams is out for the year after suffering a knee injury that forced him off the field on a cart during preseason play. An MRI followed, and the coaching staff had already signaled the news was 'not good' before the results came back.

Why it matters: This is the latest in a string of injury setbacks that have limited Adams' availability in recent seasons, and losing a full year before it even starts is a real blow to his standing among the league's top safeties. A player once viewed as a perennial All-Pro now has to prove his body can hold up again.