What happened: Jefferson will not play in Minnesota's Sunday game against Miami after being listed out with an ankle injury. The status locks in his absence before kickoff and removes the Vikings' top wide receiver from the game plan.

Why it matters: Jefferson's absence strips Minnesota's passing attack of its most established option and forces the Vikings to redistribute snaps and targets at receiver. It also extends the fallout from Jefferson's sprained ankle into Sunday's matchup with Miami.

What to watch: Minnesota's inactive list Sunday will show how it plans to Jefferson's participation next week will be the next indicator on his availability beyond Miami.