What happened: With Lamar Jackson ruled out, the immediate fantasy football projections for his primary targets and backfield have shifted. The quarterback's absence directly impacts the expected volume and efficiency for Zay Flowers, Derrick Henry, and Mark Andrews.

Why it matters: Jackson's absence fundamentally alters the offensive dynamics and scoring potential for the upcoming game. Fantasy managers are currently debating whether to sell high on production leaders like Flowers or hold through the change under center.

What to watch: Managers must finalize their starting lineups and monitor how the offense distributes touches without its primary signal-caller.