What happened: The 2026 No. 1 overall pick takes over the starting role in Week 10 after a quarterback trade. His team enters the game at 4-5.
Why it matters: The result will leave the club either 5-5 or 4-6 as it tries to stay in playoff contention.
By the numbers: ESPN Research says the previous four quarterbacks to make their first career start against a Mike Macdonald-led defense all lost, combining for no passing touchdowns and nine interceptions.
What to watch: Mendoza's passing production and ball security will be the immediate measures in his first start.