What happened: The NFL moved Chicago-Green Bay out of the featured 1:25 p.m. PT Fox window to 10 a.m. PT for Week 5. San Francisco-Seattle inherits the lead late-doubleheader slot with broader national distribution.
Why it matters: The matchup pairs the division leader against its closest pursuer for early control of the NFC West. It follows Seattle's title run through San Francisco's stadium last February.
By the numbers: San Francisco 3-0, first in NFC West; Seattle 2-1, second; Green Bay 1-2 after dropping two of three; last playoff meeting: Seattle 41, San Francisco 6.
What to watch: The teams meet in Seattle for their first game of the 2026 series.