What happened: The milestone came on his fourth touchdown pass of the night. Los Angeles hosted the Monday night matchup at SoFi Stadium.
Why it matters: Passing Dan Marino leaves Stafford alone in sixth all-time in four-touchdown games. It places his production alongside one of the league's historic volume-passing benchmarks.
By the numbers: 22 career games with four or more passing touchdowns for Stafford; 21 for Marino; sixth-most in NFL history.
What to watch: Stafford gets his next chance to build on 22 in the Rams' next outing.