What happened: The Pittsburgh Steelers have ruled out running back Rico Dowdle for Sunday with a toe injury. The Houston Texans will also be without wide receiver Nico Collins due to a hamstring issue.

Why it matters: Both teams lose critical pieces of their offensive game plans for key matchups. Pittsburgh faces a divisional test without a primary backfield option, while Houston must navigate the Colts without its top outside receiving threat.

What to watch: Pittsburgh may need to rely on Jaylen Warren, who remains questionable with a shoulder injury, while Houston evaluates its remaining receiving depth.