What happened: Kareem signed a one-year contract two days after joining a practice squad. He brings experience from four postseason appearances.
Why it matters: The transaction gives San Francisco an immediate replacement on the active roster before the 2026 season. Okuayinonu's move removes a returning contributor from the current defensive-line rotation.
By the numbers: Kareem has 41 tackles, 1.0 sack, one forced fumble and one fumble recovery across 34 regular-season games. Okuayinonu recorded 39 tackles, 3.0 sacks and one forced fumble in 15 games, including 12 starts, in 2025.
What to watch: Watch how Kareem fits into the defensive-line rotation and whether San Francisco later updates Okuayinonu's status.