49ers open practice window for Mykel Williams

2025 No. 11 pick had 20 tackles in nine games

Wire Report IntelligenceUpdated 39m1 min read

49ers have opened the practice window for DL Mykel Williams to return from the Physically Unable to Perform List. Via @AdamSchefter on X

What happened: San Francisco opened the practice window for defensive lineman Mykel Williams to return from the Physically Unable to Perform List. The former first-round pick opened the season on reserve/PUP.

Why it matters: San Francisco is 3-0 despite core injuries on both sides of the ball. Getting Williams back on the field gives the defensive line a first-round option as the regular season advances.

By the numbers: Mykel Williams, 2025 with San Francisco: 9 games, 20 tackles, 1 sack. Draft: 11th overall in 2025 out of Georgia. Timeline: placed on reserve/PUP on Aug. 30 after entering Week 1 as a longshot.

What to watch: Watch daily participation reports for progress toward activation to the 53-man roster.

Sources

@AdamSchefter 2026-09-30T21:16:21.106835+00:00

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NFLInjurySan Francisco 49ersMykel Williams

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