What happened: The Dallas Cowboys designated wide receiver George Pickens, cornerback Joey Porter Jr., and linebacker DeMarvion Overshown as inactive ahead of Sunday's matchup at Indianapolis. Pickens is sidelined with shoulder and hamstring injuries, while Porter has an ankle issue and Overshown is out with back and hamstring ailments.

Why it matters: The absences leave Dallas depleted on both sides of the ball against the Colts. Without Pickens in the passing attack and Porter in the secondary, Dallas faces significant depth tests in coverage and perimeter playmaking.

What to watch: The Cowboys and Colts kick off Sunday at 1:00 PM ET in Indianapolis.