What happened: Jacksonville beat Philadelphia in London on a 57-yard Cam Little walk-off after Ameer Abdullah returned the preceding kickoff to the 39. Philadelphia gained 232 yards of offense while playing without Saquon Barkley and Devonta Smith. The defeat followed a blown 20-10 fourth-quarter lead to Los Angeles and the departures of Lane Johnson to retirement and Cam Jurgens to Baltimore.

Why it matters: The slide leaves Philadelphia at 2-3 with an offense ranked 30th in EPA per play, 30th in passing success rate and 29th in scoring. A.J. Brown was traded to New England after a 2025 season that ended in a 23-19 wild-card loss to San Francisco, leaving Smith atop a rebuilt room with Makai Lemon, Hollywood Brown and Dontayvion Wicks. Lemon is averaging 7.2 yards per catch and Philadelphia is passing for under 190 yards per game.

What to watch: Philadelphia faces stabilizing the offensive line without Johnson and Jurgens and restoring pass-game efficiency. Availability of Barkley and Smith frames the next week of preparation.