What happened: Philadelphia ruled out wide receiver Devonta Smith for Sunday's Week 4 game against the Los Angeles Rams because of a hamstring injury. The designation closes the week with Smith unavailable two days after his status had already tightened.

Why it matters: The Eagles had already moved Smith closer to the sideline; he was listed as questionable for the Rams game earlier Thursday. Friday's ruling removes any remaining doubt and forces Philadelphia to set its receiving plan without him.

What to watch: Philadelphia's Sunday inactive list will show how it fills Smith's snaps against Los Angeles.