What happened: Ed Werder joined First Up 1050 to discuss Thursday Night Football featuring the Seattle Seahawks, evaluate the San Francisco 49ers, and assess Harrison Jr.'s outlook with the Houston Texans.

Why it matters: Seattle enters its Thursday night contest following a 32-29 divisional loss to San Francisco, while the 49ers prepare for Monday night against Washington without suspended linebacker Dre Greenlaw. In the AFC South, Houston continues integrating its offensive weapons alongside receiver Nico Collins and newly activated offensive tackle Braden Smith.

What to watch: Seattle takes the field on Thursday night while San Francisco faces Washington on Monday night.