What happened: John Lynch said Mike Evans is still to be determined after the veteran wideout tried to push through the injury and "will make every attempt" to play. Lynch added that Bosa is unlikely as he works through a calf issue, while Trent Williams may practice Thursday.

Why it matters: San Francisco is 3-0 but has already been managing injuries across the roster, so another limited week for Evans would keep that shuffle going. <a href='https://wire.report/article/nick-bosa-ruled-out-mike-evans-questionable-against-cardinal-2026-09-25'>Evans was already listed as questionable against Arizona</a>, making the next two practice reports important for the 49ers' game-week outlook.

What to watch: Watch Thursday's participation report and the final injury designations later in the week for Evans, Bosa and Trent Williams.