What happened: Patrick Mahomes and Bo Nix are on track to start Monday night's season opener between the Kansas City Chiefs and Denver Broncos. Chiefs coach Andy Reid said Tuesday that Mahomes was expected to start barring a setback. [Yahoo Sports](https://ca.sports.yahoo.com/news/patrick-mahomes-expected-start-chiefs-180442828.html)

Why it matters: Advocates of extra pressure argue that game contact tests returning quarterbacks in ways practice cannot replicate. Those favoring restraint warn that tailoring a defense to presumed limitations can backfire against a quarterback ready to operate normally.

What to watch: Watch whether either defense increases pressure early and how the quarterbacks respond to their first regular-season contact since their injuries.