What happened: Klint Kubiak attributed the designation to a knee injury. Bowers missed the opener with the same knee issue that sidelined him for Week 1.

Why it matters: Las Vegas extended Michael Mayer for three years and $45 million with $30 million guaranteed on Sept. 12, securing another tight end. A second absence for Bowers would leave the Raiders thin at the position early in the regular season.

What to watch: Sunday's inactive list will confirm whether Bowers is available.