What happened: Jeremy Peña left Houston's game with a right hamstring cramp. The Astros announced the exit during the contest, removing their everyday shortstop from the lineup.

Why it matters: Peña is a central piece of Houston's infield and top of the order, so any leg issue is worth tracking closely. A hamstring cramp is typically minor, but it raises questions about whether he is available for the next game or needs precautionary rest.

What to watch: Watch for a post-game update from the Astros on Peña's status and whether he is in the lineup for the next game. The distinction between a cramp and a strain will determine if any roster move is needed.