What happened: Washington Commanders rookie quarterback Athan Kaliakmanis entered Sunday's game in London against the Indianapolis Colts to make his NFL debut. He took over the offense after starting quarterback Marcus Mariota headed to the locker room.

Why it matters: The sudden personnel change thrusts the 223rd overall pick of the 2026 NFL Draft into action as the Commanders navigate a battered roster. Washington is already playing without Jayden Daniels, who suffered a dislocated left elbow earlier this season, and star receiver Terry McLaurin, who was ruled out with a hamstring injury.

What to watch: The Commanders will evaluate Mariota's knee to determine his availability for the remainder of the contest. Kaliakmanis will run the offense with Washington defending an early 6-0 lead.