What happened: Buffalo made the Week 5 trip west for a Monday night matchup with Los Angeles. The road test arrived amid renewed 2026 expectations for the Bills.

Why it matters: Early-October prime-time results help define AFC positioning before the midseason stretch. Buffalo already finalized a two-year extension for linebacker Joe Andreessen with $3 million guaranteed.

What to watch: Buffalo turns to its next week of preparation after leaving Los Angeles.