What happened: Week 2 opens with Buffalo visiting Detroit after the Bills leaned into a 60 to 40 pass run split in their opener. That same game also showed Allen attacking downfield more than he typically has in recent seasons. Buffalo's defense is adjusting to a new 3 to 4 base, but this matchup still starts with what its offense can dictate.

Why it matters: Buffalo used play action on 41 percent of its Week 1 plays, which forces second level defenders to hesitate before Allen even throws. A 40 percent rate of 13 personnel makes the run, the quarterback keep, and quick tight end matchups live on the same snap. Allen's 81 career rushing touchdowns, already the most by any quarterback, make that stress even harder to solve near the goal line.