What happened: Rashee Rice (hamstring and knee) and offensive lineman Jaylon Moore (concussion protocol) missed every practice session this week before drawing Friday's out designation. Running back Brashard Smith also joined the inactive list after suffering a hamstring injury during Thursday's practice.

Why it matters: Kansas City enters the matchup holding the top conference seed on a five-game winning streak, while Seattle arrives on a two-game skid at the eighth seed. Losing Smith alongside Rice and Moore depletes the Chiefs across three offensive position groups simultaneously.

What to watch: Practice squad running back Jaydn Ott, a rookie out of Oklahoma, is expected to be elevated to Kansas City's active roster ahead of Sunday's game against Seattle.