What happened: Nico Collins and Zay Flowers are officially sidelined for Week 2 with hamstring injuries. Joe Burrow and Puka Nacua carry questionable designations into Sunday.

Why it matters: The confirmed absences remove primary receiving targets from the field early in the regular season. Burrow's condition adds uncertainty under center, though he previously stated he intends to play through the issue.

What to watch: Official inactive lists released 90 minutes before kickoff will finalize the availability for Burrow and Nacua.