What happened: The New England Patriots travel to the new Highmark Stadium today to take on the 6-0 Buffalo Bills. The visitors have already ruled out defensive tackle Christian Barmore, cornerback Christian Gonzalez, and rookie Channing Canada.

Why it matters: Buffalo is averaging 31.5 points per game during its six-game winning streak. The Patriots are allowing 20.3 points per contest, but missing multiple defensive starters makes containing this high-scoring offense nearly impossible.