What happened: Jacksonville Jaguars head coach Liam Coen confirmed Monday that defensive tackle DaVon Hamilton and safety Eric Murray will miss the remainder of the season with injuries. Hamilton suffered a torn quadriceps during Sunday's victory over the Indianapolis Colts.

Why it matters: The dual losses deplete Jacksonville's defensive rotation as the team contends for playoff positioning at 5-2 through seven games in 2026. Murray had logged 15 tackles across five games this season, previously earning praise from Coen as a pro's pro on defense.

What to watch: The Jaguars evaluate defensive depth ahead of the Nov. 10 trade deadline to address vacancies along the interior front and secondary.