What happened: Mays joined Detroit in March as an unrestricted free agent. His contract runs three years and carries a $25 million value.
Why it matters: The injury interrupts Mays' transition to Detroit as the club rebuilds the middle of its offensive line. His absence puts the Lions' center depth under an immediate preseason test.
By the numbers: Mays has appeared in 52 career games with 27 starts while allowing 5.0 sacks.
What to watch: Detroit's practice rotation at center will show how it plans to absorb the loss. Dan Campbell's next update could provide a firmer timetable.