What happened: Washington Commanders quarterback Marcus Mariota will not return to Sunday's game due to a knee injury. The team officially downgraded him to out during the matchup against the Indianapolis Colts.

Why it matters: The setback forces Washington to finish the contest with rookie Athan Kaliakmanis under center. Mariota was leading the offense in place of Jayden Daniels, who was sidelined for the trip to London.

What to watch: Washington will provide a medical update on the quarterback following the conclusion of the game.