What happened: Defensive coordinator Raheem Morris confirmed Bosa's availability Tuesday, saying, “He's going to play.” Bosa resumed practice Sept. 1 after recovering from a right ACL injury.
Why it matters: The return restores San Francisco's leading edge presence for the start of the regular season. It also completes Bosa's recovery from the third ACL injury of his career.
By the numbers: Bosa missed the final 14 games of the 2025 season after suffering the injury in Week 3.
What to watch: His workload and effectiveness after the extended absence will be the next measures of his recovery.