What happened: Philadelphia enters Week 6 without quarterback Jalen Hurts, while running back Saquon Barkley and wide receiver Devonta Smith remain uncertain to play, per Field Yates. During Thursday's open practice window, Barkley was not spotted on the field and Smith warmed up without a helmet, per Tim McManus.

Why it matters: Losing Hurts for Sunday already removes the centerpiece of an offense operating behind a banged-up and struggling offensive line. Any additional absence for Barkley or Smith would leave Philadelphia without its top playmakers in the passing and rushing attacks.

What to watch: Philadelphia's Friday practice participation and final Week 6 injury designations will clarify whether Barkley and Smith are cleared for Sunday.