What happened: Clemson travels to Tallahassee for a Halloween night game after a home loss to Virginia Tech. Ousmane Kromah is out for the season and Samuel Singleton is also hurt, leaving Wisner in line for a larger role.

Why it matters: The running game had been Florida State's offensive strength, with quarterback Ashton Daniels also a threat on the ground. Another loss would leave Clemson with less room to recover this season.

What to watch: Saturday's game will test how much of the rushing workload Wisner can take and whether Clemson can contain Daniels.