What happened: ESPN's Dan Graziano issued an injury update on the 49ers and Rams ahead of their Week 1 opener in Melbourne, Australia. San Francisco kept edge rusher Nick Bosa out of practice entirely, while a receiver worked on a side field in a limited capacity.

Why it matters: The absences come after Bosa returned for the 49ers' final Rams prep session earlier in the week, underscoring how fluid San Francisco's health picture is heading into the opener. Both teams have already committed their full rosters to the trip, raising the stakes on which starters are actually available.

What to watch: The 49ers and Rams kick off Week 1 in Melbourne on Sept. 10.