What happened: Kickoff is Sunday, September 13, at 1 p.m. ET on CBS and Paramount+.
Why it matters: The AFC matchup gives Buffalo an early opportunity to collect a conference win.
By the numbers: Both teams enter the 2026 opener 0-0. [Bills game center](https://www.buffalobills.com/game-day/2026/reg-week1/bills-at-texans/)
What to watch: Final game statuses and Sunday's inactive lists will establish each team's available lineup.