Nick Bosa is expected to miss a few weeks after pulling his calf in practice on Thursday. How big of a loss is this fo Via @NFLonFOX on X

What happened: Nick Bosa pulled his calf during Thursday practice. San Francisco opens the expected absence Sunday against the Cardinals.

Why it matters: Bosa anchors San Francisco's edge rotation as a five-time Pro Bowl selection. His absence tests depth during the early regular-season stretch.

What to watch: Watch practice participation and Sunday inactives for status clarity.

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