What happened: Houston's defense is preparing for the Chargers and quarterback Justin Herbert. Texans defensive end Will Anderson has called the Chargers offense "a good challenge" for the unit.

Why it matters: The Chargers lost 24-9 at the Los Angeles Rams on Nov. 1 and have not won through seven games. Houston is coming off a 27-21 loss to the New York Giants on Oct. 25.

What to watch: The NFL trade window closes Nov. 10 at 4 p.m. ET, and the Chargers have kept Herbert off the table.