What happened: Ricky Pearsall will undergo surgery on a lingering PCL injury and move to season-ending injured reserve. Bryan Bresee tore his ACL during a non-contact practice play last week and will also have surgery.

Why it matters: Christian Kirk's hamstring ailment further strains San Francisco's receiving depth after Deebo Samuel returned on a reported one-year deal. New Orleans must replace a 2023 first-round pick who started all 17 games last season.

What to watch: Watch whether San Francisco adds another receiver and how New Orleans reshapes its defensive-line rotation before preseason games.